Fig. 7 | Signal Transduction and Targeted Therapy

Fig. 7

From: Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis

Fig. 7

Erianin exerts its antitumor effects in vivo. a Representative image of H460 xenograft tumors after erianin treatment. b Tumor volume in each group. Data are expressed as the means ± standard deviations (SDs). c Scheme of tumor inoculation and systemic injection. d Bioluminescent imaging of disseminated H460-luc orthotopic xenograft tumors at different time points posttreatment, and representative images of H460-luc orthotopic xenograft lung tumors after erianin treatment. e Fold change in the average radiance per mouse after normalization to the day 0 tumor burden as determined by bioluminescent imaging, **p < 0.01. f Fold change in the average radiance per mouse at the experimental endpoint (day 12) for each treatment group (mean ± SEM), **p < 0.01

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