Fig. 5 | Signal Transduction and Targeted Therapy

Fig. 5

From: The interactions between cGAS-STING pathway and pathogens

Fig. 5

Pathogen evasions from cGAS-STING pathway. Different strategies are adopted by HSV-1 and HIV-1 to evade from the surveillance of the cGAS-STING pathway. Whereas HSV-1 mainly encodes a variety of proteins to counter key signal transduction processes of the cGAS-STING pathway, HIV-1 utilizes cellular autonomous restriction factors and transport systems to limit exposure of its viral DNA to cGAS. The viral proteins encoded by HSV-1 are shown in the same colour as HSV-1 capsids

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