Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Mitomycin C enhanced the efficacy of PD-L1 blockade in non-small cell lung cancer

Fig. 1

Upregulation of PD-L1 expression in tumor cells following MMC treatment. a Western blot analysis of PD-L1 protein expression in three different NSCLC cells (A549, H1299, and H460) after 48-h treatment with different chemotherapeutic drugs. b, c Representative images showing the western blot analysis of PD-L1 protein expression of the indicated NSCLC cells after treatment with MMC at different concentrations and for different duration. d Relative PD-L1 protein expression (normalized with GAPDH) in NSCLC cells after 72-h treatment of MMC (0–0.4 μM). Results are presented as mean ± SD. ***p < 0.001

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