Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: The key roles of cancer stem cell-derived extracellular vesicles

Fig. 4

Cancer stem cells-derived EVs promote the formation of tumor immunosuppression microenvironment. EVs secreted by CSCs exhibited a tumor immunosuppression microenvironment through inhibiting the survival and proliferation of effector T cells and dendritic cells, as well as inducing the production of M2 macrophage, immunosuppressive monocytes, and neutrophils

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