Fig. 3

The dynamic study for critical patient 1 before and after improvement. a TSNE plots of cell types identified in patients with dynamic study (P1-1, P1-2, P1-3, P2-1, P2-2,m P2-3, P3-1, P3-2,P6-1, P6-2, P7-1, P7-2, P9-1, P9-2, P10-1, and P10-2). b TSNE plots of P1-1 (in critical condition) and P1-2 (in improvement condition), showing the cell type distribution in the two samples. c TSNE plots of P1-2 and P1-3 (in cured condition), showing the cell type distribution in the two samples. d Comparisons of all the cell subtypes of P1-1, P1-2, and P1-3. e Log2 fold changes of the UMI counts of the genes involved in viral mRNA translation, IFN-I, MAPK targets, and ferroptosis between P1-1 and P1-2. Each point represents a different cell subtype. f Log2 fold changes of the UMI counts of the genes involved in viral mRNA translation, IFN-I, MAPK targets, and ferroptosis between P1-2 and P1-3. Each point represents a different cell subtype