Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: HLA-mismatched allogeneic adoptive immune therapy in severely immunosuppressed AIDS patients

Fig. 2

Effects of AAIT on peripheral blood CD4+/CD8+ T-cell counts and HIV RNA in severely immunosuppressed AIDS patients. a The trend of CD4+ T-cell counts in severely immunosuppressed AIDS patients. b Changes in CD4+ T-cell counts in each of the 12 severely immunosuppressed AIDS patients. c The trend of CD8+ T-cell counts in severely immunosuppressed AIDS patients. d Changes in CD8+ T-cell counts in each of the 12 severely immunosuppressed AIDS patients. e The trend of CD4/CD8 ratio in severely immunosuppressed AIDS patients. f Changes in CD4/CD8 ratio in each of the 12 severely immunosuppressed AIDS patients. g The change of HIV RNA in patients receiving ART before AAIT (n = 7). h The change of HIV RNA in patients receiving AAIT before ART (n = 5). For patient 05-Z, the AAIT was 20 days before ART. For patient 08-D, the AAIT was 8 days before ART. For patient 10-L, the AAIT was 7 days before ART. For the other two patients, the AAIT was 2 days before ART. The arrows represent the time of ART start

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