Table 1 Baseline characteristics of 12 severely immunosuppressed AIDS patients enrolled in AAIT
From: HLA-mismatched allogeneic adoptive immune therapy in severely immunosuppressed AIDS patients
Patient | Gender | Age (years) | Transmission route | Laboratory examinations | Viral nucleic acid | ART relative to initiation of AAIT (days) | Times of transfusion | Dose of each transfusion 108/kg | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HIV RNA (copies/ml) | CD4 (cells/μl) | CD8 (cells/μl) | WBC (109/L) | RBC (1012/L) | PLT (109/L) | HGB (g/L) | ALT (U/L) | AST (U/L) | Cre (μmol/L) | CMV (IU/ml) | EBV (IU/ml) | HBV (copies/ml) | HCV (copies/ml) | |||||||
01-W | M | 36 | Heterosexual | <20 | 33 | 602 | 5.43 | 3.37 | 352 | 105 | 9 | 18 | 81 | <100 | 2.58E+02 | <40 | <50 | −104 | 5 | 3/2.5/2.5/ 2.5/2.5 |
02-Z | M | 28 | Heterosexual | 2.17E+04 | 7 | 227 | 1.31 | 2.59 | 136 | 78 | 20 | 42 | 53 | <100 | 1.97E+02 | <40 | <50 | −28 | 4 | 3/3.1/3/3 |
03-G | M | 18 | Homosexual | 2.32E+06 | 9 | 688 | 3.15 | 4.18 | 131 | 121 | 58 | 35 | 74 | <100 | <100 | <40 | <50 | −5 | 3 | 3/3.5/2.6 |
04-D | M | 35 | Homosexual | 1.62E+02 | 1 | 40 | 1.75 | 3.05 | 170 | 87 | 18 | 24 | 63 | 4.17E+02 | <100 | <40 | <50 | −58 | 3 | 2.6/2.9/2.9 |
05-Z | M | 29 | Homosexual | 8.88E+05 | 32 | 778 | 1.88 | 4.41 | 142 | 127 | 95 | 68 | 88 | <100 | <100 | <40 | <50 | +20 | 3 | 3/2.6/2.6 |
06-L | M | 44 | Homosexual | 1.01E+06 | 11 | 90 | 6.25 | 4.38 | 394 | 128 | 40 | 38 | 62 | 1.74E+04 | 6.64E+02 | <40 | <50 | −10 | 2 | 3/2.5 |
07-X | M | 34 | Unknown | 1.76E+07 | 4 | 590 | 3.16 | 4.44 | 239 | 127 | 29 | 46 | 84 | <100 | <100 | <40 | <50 | −6 | 3 | 3.5/3/3 |
08-D | M | 54 | Homosexual | 2.20E+05 | 10 | 268 | 7.09 | 4.66 | 325 | 151 | 33 | 18 | 85 | <100 | <100 | <40 | <50 | +8 | 2 | 3/3 |
09-L | F | 31 | Heterosexual | 1.25E+07 | 13 | 474 | 4.27 | 3.96 | 87 | 127 | 94 | 98 | 47 | 1.27E+03 | <100 | <40 | <50 | +2 | 3 | 3.3/3.2/3.2 |
10-L | M | 35 | Heterosexual | 4.47E+05 | 20 | 374 | 4.32 | 3.76 | 278 | 121 | 47 | 27 | 74 | <100 | <100 | <40 | <50 | +7 | 2 | 3.5/2.6 |
11-S | M | 39 | Unknown | 2.53E+05 | 7 | 258 | 2.29 | 5.83 | 281 | 165 | 59 | 39 | 69 | <100 | <100 | <40 | <50 | −3 | 2 | 3.1/3 |
12-L | M | 27 | Homosexual | 8.86E+04 | 15 | 459 | 2.87 | 4.63 | 106 | 133 | 112 | 32 | 72 | 3.04E+04 | <100 | <40 | <50 | +2 | 2 | 3.3/3 |
