Table 1 Ribosomal proteins and human disease

From: Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy

Ribosomal protein

Entrez gene ID

Human disease

References

Developmental disease

Cancers

RPS7

6201

DBA

Prostate cancer, colorectal cancer, breast cancer, ovarian cancer

305,306,307,308,309

RPS10

6204

DBA

 

310

RPS14

6208

Del(5q) MDS

 

149

RPS15

6209

DBA

CLL

305,311

RPS15A

6210

DBA

lung, glioblastoma, gastric, liver and colorectal cancer

217,218,219,220,221,222,312

RPS17

6218

DBA

Colorectal cancer

313,314

RPS19

6223

DBA

Epidermoid carcinoma

315,316

RPS20

6224

 

Hereditary nonpolyposis colorectal cancer, gastric cancer

317,318

RPS23

6228

Brachycephaly, trichomegaly and developmental delay

 

319

RPS24

6229

DBA

Colorectal

320,321

RPS26

6231

DBA

 

310

RPS27

6232

DBA

Melanoma

322,323

RPS28

6234

DBA

 

145

RPS29

6235

DBA

 

324

RPSA

3291

Isolated congenital asplenia

Pancreatic cancer

325,326

RPL3L

6123

Autosomal dominant polycystic kidney disease

 

327

RPL5

6125

DBA

T-ALL, melanoma, multiple myeloma, glioblastoma, breast cancer

202,305

RPL9

6133

DBA

Colorectal cancer

328,329

RPL10

6134

Autism; X-linked syndromic mental retardation 35

T-ALL, epithelial ovarian cancer

205,208,330,331

RPL11

6135

DBA

T-ALL, melanoma, gastric cancer

202,205,305,332

RPL13

6137

Spondyloepimetaphyseal dysplasia

 

333

RPL15

6138

DBA

Breast cancer, pancreatic cancer, colon cancer, gastric cancer

334,335,336,337,338

RPL18

6141

DBA

 

339

RPL21

6144

Hypotrichosis 12

Pancreatic cancer

340,341

RPL22

6146

 

T-ALL, gastric cancer, endometrial cancer, colorectal cancer, adrenocortical carcinoma

209,210,211,212,213,214,342

RPL23A

6147

 

Endometrial cancer

202

RPL26

6154

DBA

 

343

RPL27

6155

DBA

Nasopharyngeal carcinoma

322,344

RPL31

6160

 

Prostate cancer

345

RPL34

  

Esophageal cancer, Non-small cell lung cancer, esophageal cancer, gastric cancer, pancreatic cancer, glioma cells, osteosarcoma, cervical cancer

346,347,348,349,350,351,352

RPL35

11224

DBA

neuroblastoma

339,353

RPL35A

6165

DBA

 

354

RPL36

25873

 

Glioma, hepatocellular carcinoma, colorectal cancer

355,356,357

  1. CLL chronic lymphocytic leukemia, T-ALL T-cell acute lymphoblastic leukemia