Fig. 1: Monoclonal antibody 3E8 and recombinant S1-subunits or RBD from different coronaviruses (and SARS-CoV-2 mutant variants) bound to recombinant human ACE2 protein.
From: ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker

a Binding of 3E8 to His-tagged recombinant human ACE2 protein as measured by ELISA. b Binding of 3E8 to His-tagged human ACE2 as measured by BLI. c–g Bindings of recombinant S1-subunits or RBD (in f only) from multiple coronaviruses and SARS-CoV-2 mutated variants to Fc-tagged recombinant human ACE2 protein as measured by ELISA. h The EC50 values of recombinant S1-subunit bindings to human ACE2