Table 1 Baseline characteristics of the patient population

From: Melatonin enhances radiofrequency-induced NK antitumor immunity, causing cancer metabolism reprogramming and inhibition of multiple pulmonary tumor development

Characteristics

RFA+MLT (n = 21)

Surgery (n = 21)

P value

Age (years)

   

 Mean (SD)

58.48 (10.96)

58.47 (11.36)

0.9977

 Range (years)

38–82

36–78

Gender (n, %)

  

1

 Men

8 (38.10)

8 (38.10)

 

 Women

13 (61.90)

13 (61.90)

 

Smoking (n, %)

3 (14.29)

3 (14.29)

1

Position (n, %)

 R.U.L.

9 (42.86)

7 (33.33)

0.2389

 R.M.L.

1 (4.76)

1 (4.76)

 

 R.L.L.

3 (14.29)

5 (23.81)

 

 L.U.L.

6 (28.57)

2 (9.52)

 

 L.L.L.

2 (9.52)

6 (28.57)

 

Dominant tumor size (cm)

   

 Mean

0.88 (0.22)

0.89 (0.17)

0.9028

 Range (cm)

0.7–1.3

0.7–1.2

 

Dominant tumor feature (n, %)

  

0.5178

 pGGO

13 (61.90)

15 (71.43)

 

 mGGO

8 (38.10)

6 (28.57)

 

Spicule sign (n, %)

  

0.6825

 With

3 (14.29)

4 (19.05)

 

 None

18 (85.71)

17 (80.95)

 

Pathology (n, %)

  

1

 AAH

10 (47.62)

10 (47.62)

 

 AIS

11 (52.38)

11 (52.38)

 

Lung function

   

 FEV1 (L)

2.61 (0.85)

2.39 (0.72)

0.3709

 FEV1 measured/anticipated %

96.26 (16.36)

88.14 (7.26)

0.0441

 VCMAX (L)

3.16 (0.90)

2.83 (0.61)

0.1719

 VCMAX measured/anticipated %

93.95 (12.31)

88.20 (8.58)

0.0867

  1. SD standard deviation, pGGO pure ground-glass opacities, mGGO mixed ground-glass opacities, AAH atypical adenomatous hyperplasia, AIS adenocariconoma in situ, FEV1 forced expiratory volume in 1 s, VCMAX maximal vital capacity