Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: The self-assembled nanoparticle-based trimeric RBD mRNA vaccine elicits robust and durable protective immunity against SARS-CoV-2 in mice

Fig. 2

Formulation and physical properties of liposomal nanoparticles (LNPs) for codelivery. a LNPs were synthesized from PEG-lipid (1.5 mol/mol), DSPC (10 mol/mol), ionizable lipid (50 mol/mol), and cholesterol (38.5 mol/mol) at a specific ratio. b The particle size, uniformity, and zeta potential of the LNPs were measured by a Malvern particle size instrument. c TEM images of the LNPs (scale bar, 100 nm). d The mRNA expression of the LNPs (T-RBD and TF-RBD proteins) in HEK293T cells was analyzed by western blot

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