Table 3 SARS-CoV-2 variants features and CD147 antibody inhibition rate

From: CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma

Virus name

Country of origin

Mutations (AA)

Meplazumab inhibition rate (60 μg/ml)

Source

SARS-CoV-2

China

 

68.7%

National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention

Alpha

United Kingdom

HV69-70 Del, Y145 Del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H

75.7%

Beta

South Africa

D80A, D215G, LAL242–244 Del, E484K, K417N, N501Y, D614G, A701V

52.1%

Gamma

Brazil

L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F

52.1%

Delta

India

T19R, T95I, G142D, L452R, T478K, D614G, P681R, D950N, R158del

62.3%

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