Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: Targeting PI3K/Akt signal transduction for cancer therapy

Fig. 2

Downstream effectors of the PI3K/Akt signaling pathway and their cellular functions. The activation of Akt signaling can promote (arrows) or inhibit (blocking arrows) the phosphorylation of downstream effectors. Downstream regulation by Akt contributes to many cellular processes, including tumor growth, tumor survival, tumor cell proliferation, cancer immunity, cancer metabolism and cancer angiogenesis

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