Fig. 6
From: Inactivated SARS-CoV-2 induces acute respiratory distress syndrome in human ACE2-transgenic mice
Dexamethasone and passive antibody therapy alleviated the progress of ARDS induced by inactivated SARS-CoV-2 in hACE2 mice. a–f Reduced body-weight loss (a), images of lung tissues (b), measurement of lung weight (c), images of H&E staining (d), pulmonary pathological scores for mice according to the scoring system (e) and analysis of cytokines or chemokines in sera by a customized Luminex Mouse Cytokine 23-plex (f) on 3 dpi in hACE2 mice when treated with dexamethasone. g–j Images of lung tissues (g), measurement of lung weight (h), images of H&E staining (i) and pulmonary pathological scores for mice according to the scoring system (j) on 3 dpi in hACE2 mice when passively immunized with sera from S1 protein immunized mice. Data represent the mean ± SEM. Significance is indicated by: ns, no significance; *P ≤ 0.05
