Fig. 2

ARCoV vaccination prevents SARS-CoV-2 replication and secretion in cynomolgus macaques. Nasal swab (a) specimens were obtained on day 2, 4, and 6 after challenge. Trachea (b) and lung (c) specimens were obtained on day 7 after challenge. Viral load was assessed by analysis of SARS-CoV-2 genomic RNA (gRNA) and subgenomic RNA (sgRNA). Data are shown as mean ± SEM. The dashed lines indicate the detection limit of this assay