Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma

Fig. 4

PROCR triggers mitochondrial fission through activating lipid synthesis. a Mitochondrial dynamics labeled by MitoTracker staining in tumor cells with APC or C75 treatment. C75, FASN inhibitor. Scale bar denotes 10 µm. b Quantification of the proportion of mitochondria with three different statuses. The relative number of mitochondria with different statuses was counted from about 100 cells in each treatment group. **P < 0.01. c Western blot examination of genes expression essential for mitochondrial fission in NPC cells with different treatment

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