Fig. 12
From: Therapeutic peptides: current applications and future directions

Mechanism of natriuretic peptide (NPs) regulation. Atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) regulate cardiac and vascular homeostasis through binding to their receptors (NPR-A, -B and -C) to reduce sympathetic tone, fibrosis and renin secretion to treat cardiovascular diseases