Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: Identification of the receptor of oncolytic virus M1 as a therapeutic predictor for multiple solid tumors

Fig. 4

MXRA8 is abundant in human tumor tissues but shows different expression levels among patients. a An overview of the RNA-seq data showing the MXRA8 expression levels in human tumor tissues according to the TCGA database. b Pan-analysis of the mRNA expression levels of MXRA8 in tumor tissues compared with the corresponding normal tissues in the TCGA database by paired t-test (HNSC, n = 43; LUAD, n = 60; KIRC, n = 58; THCA, n = 59). Each dot represents a single patient. c The expression levels of MXRA8 in tumor tissues from the TCGA database compared with those in the corresponding normal tissues from the TCGA and GTEX databases by two-tailed unpaired t-test. (GBM, n = 165 tumor versus 1146 normal tissues; PAAD, n = 178 versus 165; LAML, n = 173 versus 444). d, e RNA-scope detection of RNA in renal cancer (d) and glioma (e) with probes against MXRA8. Scale bars: 20 μm. f, g The expression of MXRA8 in renal cancer and glioma was measured by RT-qPCR. n.d., not detectable; *P < 0.05; **P < 0.01; ***P < 0.001

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