Fig. 3
Correlation between hyaluronan and pulmonary lesions in COVID-19 patients with a low level of hyaluronan (HA < 48.43 ng/mL). a, b Scatter plot showing relation on the mass (a) and volume (b) of GGO against hyaluronic acid. c, d Scatter plot showing relation on the mass (c) and volume (d) of the consolidation region against hyaluronic acid. Mass and volume of pulmonary lesions were calculated via the automatic lung segmentation technology of AI based on CT images of severe COVID-19 patients. GGO was defined a range from −750 HU to −300 HU, and the consolidation region was defined from −300 HU to 50 HU. Two-tailed Spearman’s correlation analysis was performed to identify the relation of pulmonary lesions against hyaluronic acid
