Fig. 4

Hyaluronan directly induces GGO and consolidation in adult mice. Represented CT images of lungs in mice with different treatments are shown. Adult C57BL/6 mice were used to assess whether hyaluronic acid induces pulmonary lesions. We directly delivered hyaluronan (200–400 kDa) to the trachea (n = 3), and 1× PBS treatment was as the control group (n = 3). Then, we monitored the lungs of mice in two groups via QuantumGX microCT at the fourth day