Table 4 Selective clinical trials of PSMA-targeted agents
From: Targeting signaling pathways in prostate cancer: mechanisms and clinical trials
Drug | Target | Condition | Status | Phase | NCT identifier |
|---|---|---|---|---|---|
177Lu-PSMA-617 | PSMA | mCRPC | Unknown | 2 | NCT03392428 |
177Lu-PSMA-617 | PSMA | mCRPC | Recruiting | 3 | NCT04689828 |
225Ac-PSMA-617 | PSMA | PCa, CRPC | Recruiting | 1 | NCT04597411 |
177Lu-J591 | PSMA | Metastatic PCa | Completed | 2 | NCT00195039 |
MLN2704 | PSMA | mCRPC | Completed | 1/2 | NCT00070837 |
PSMA-MMAE | PSMA | mCRPC | Completed | 2 | NCT01695044 |
MEDI3726 | PSMA | mCRPC | Completed | 1 | NCT02991911 |
BIND-014 | PSMA | mCRPC | Completed | 2 | NCT01812746. |
68Ga-PSMA-11 | PSMA | PCa | Completed | 3 | NCT03803475 |
68Ga-PSMA-617 | PSMA | PCa | Completed | 2 | NCT03604757 |
18F-PSMA-1007 | PSMA | PCa | Completed | 3 | NCT04102553 |
99mTc-MIP-1404 | PSMA | PCa | Completed | 3 | NCT02615067 |
CART-PSMA-TGFβRDN | PSMA | mCRPC | Not yet recruiting | 1 | NCT04227275 |
PD1-PSMA-CART | PSMA | CRPC | Recruiting | 1 | NCT04768608 |
LIGHT-PSMA-CART | PSMA | CRPC | Suspended | 1 | NCT04053062 |
P-PSMA-101 CAR-T | PSMA | PCa | Recruiting | 1 | NCT04249947 |
