Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Engineered virus-like particles: paving the way for effective somatic genome editing

Fig. 1

Illustration of structure and engineering approaches of virus-like particles (eVLPs) and the potential applications of v4 BE-eVLPs. a The engineering strategies to improve BE-eVLPs for somatic genome editing. Four generations of BE-eVLPs were produced in the study by optimizing cleavable linker, gag–BE fusion localization, and gag–BE:gag-pro-pol stoichiometry. b The production of v4 BE-eVLPs and its potential in vivo applications. Adapted with permission.1 Copyright 2022, Elsevier

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