Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: Mesenchymal stromal cells alleviate acute respiratory distress syndrome through the cholinergic anti-inflammatory pathway

Fig. 4

Effects of α7nAChR agonists in the treatment of LPS-induced lung injury. a The therapeutic effects of peripheral nAChR agonist monepantel and the peripheral nAChR antagonist vinblastine in acute lung injury were investigated. b Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. c The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. d CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6. e Representative H&E staining was performed on lung samples from each group. Photographs of at least 6 sections of each tissue sample were taken. Scale bars, 100 μm. f The degree of lung injury was calculated and quantitatively analyzed according to the results of H&E staining, and the infiltration of leukocytes into BALF was compared among the groups; n = 6. g CXCL15, IL-1β, TNF-α, IL-6 ELISA kits were used to determine BALF inflammatory concentrations; n = 6

Back to article page