Table 1 Characteristics of the patients from control and lobeline groups

From: Mesenchymal stromal cells alleviate acute respiratory distress syndrome through the cholinergic anti-inflammatory pathway

 

Control group (n = 6)

Lobeline group (n = 10)

Age, years

59 (12)

60 (13)

Sex

 Female

2 (33.3%)

4 (40%)

 Male

4 (66.7%)

6 (60%)

Sequential Organ Failure Assessment score

15.7 ± 3.09

12.9 ± 2.21

Time from ICU admission to ARDS diagnosis, days

2.91 (1.69)

3.5 (1.5)

Time from intubation to ARDS diagnosis, days

1.25 (0.56)

1.9 (0.83)

Cause of ARDS

 Pneumonia

2 (33%)

4 (40%)

 Sepsis

1 (17%)

4 (40%)

 Aspiration

0

1 (10%)

 Trauma

1 (17%)

1 (10%)

 Others

2 (33%)

0

Degree of Lung severity, number of patients

 Moderate (100 < PaO2/FiO2 ≤ 200)

5

9

 Severe (PaO2/FiO2 ≤ 100)

1

1

PaO2/FiO2, mm Hg

133 (33.41)

143 (29.92)

Tidal volume, mL per predicted bodyweight

6.4 (0.32)

6.6 (0.48)

Respiratory rate, breaths per min

18.5 (1.38)

21.1 (6.39)

Positive end-expiratory pressure, cm H2O

10.2 (0.90)

11.1 (2.04)

Inspiratory plateau pressure, cm H2O

26.3 (1.11)

28.3 (3.19)

  1. Data are n (%), mean (SD), unless otherwise stated