Fig. 5 | Signal Transduction and Targeted Therapy

Fig. 5

From: A potent neutralizing antibody provides protection against SARS-CoV-2 Omicron and Delta variants via nasal delivery

Fig. 5

Determination of the prophylactic dose of 58G6 against Omicron in the hamster model. a Animal experimental scheme. Group 1, 10 mg/kg 58G6 (3-dose for i.n.); Group 2, 5 mg/kg 58G6 (3-dose for i.n.); Group 3, 2 mg/kg 58G6 (3-dose for i.n.); Group 4, 10 mg/kg 58G6 (1-dose for i.p.); Group 5, control group without 58G6. b Viral RNA copies in respiratory tracts of hamsters challenged with the Omicron variant at 3 dpi. c The number of infectious viruses (PFUs) was measured in the respiratory tract at 3 dpi by the viral plaque assay in Vero E6 cells. Bars indicate the mean ± SD.

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