Fig. 5 | Signal Transduction and Targeted Therapy

Fig. 5

From: Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism

Fig. 5

Fecal microbial transplantation from donor mice altered the intestinal metabolic composition and metabolic pathways of transplanted mice. a PCA of fecal metabolites from FMT, Control, and Donor mice. b Heatmap of metabolites identified in fecal samples. c Volcano plot of metabolites identified in fecal samples. Volcano plots are depicted with the fold change of each metabolite and the q value was calculated by performing a t-test and corrected by the false discovery rate. d, e Pathway enrich analysis of metabolites from Donor and Control mice, and FMT and Control mice. f, g Relative abundance of linoleic acid and stearic acid in fecal metabolites. Data presented as mean ± SD on relevant graphs. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.005 (one-way ANOVA). Control (n = 7), FMT (n = 7), and Donor (n = 6)

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