Fig. 3
From: Targeting integrin pathways: mechanisms and advances in therapy

Classification, distribution, and ligands of integrins. The inner ring shows the 24 integrins that are composed of 17 α subunits and 8 β subunits. They are divided into four categories, namely, RGD-binding integrins, leukocyte cell-adhesion integrins, collagen-binding integrins, and laminin-binding integrins, according to their distribution, ligand specificity, and functions. The middle ring shows the distribution of integrins in different cell types. The outer ring indicates the ligands bound by different types of integrins