Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP

Fig. 4

ATP-bound inward-facing and outward-facing structures of ABCD1. a, c, e, d Cartoon structures representing ABCD1 in complex with ATP in outward-facing state. a, e View from the peroxisome lumen side and cytosol; c side view. g Zoomed-in view of the ATP-binding site. b, d, f, h Cartoon representations of ABCD1 in the complex of ATP in inward-facing state, viewed from a similar orientation as the outward-facing structure on the left

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