Fig. 2 | Signal Transduction and Targeted Therapy

Fig. 2

From: CRISPR/Cas9 therapeutics: progress and prospects

Fig. 2

Schematic diagram of DNA strand cleavage tools. a Cas9 cleaves DNA double strands to form flat ends. b Cas9 nickase (Cas9n) cleaves the single DNA strand. c Cas12a cuts DNA double strands to form sticky ends. d Cas13a recognizes and cleaves RNA strands. (Figure was created with Biorender.com)

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