Table 1 Methods to study epigenomic and epigenetic states
From: Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
Methods | Purposes |
|---|---|
ChIP-seq | Studying protein/DNA-binding and histone-modification sites in a genome-wide manner |
ISH-PLA | Detecting histone modifications at specific gene loci in single cells |
DNase-seq | Mapping Deoxyribonuclease I hypersensitive sites (DHSs) |
ATAC-seq | Sequencing regions of loosely packaged chromatin through transposition of markers |
FAIRE-Seq | Sequencing the DNA unbound by chromatin proteins |
MNase-seq | sequencing regions of DNA bound by histones or other chromatin-bound proteins |
BS-Seq | 5mC detection |
oxBS-Seq | Quantitative mapping of 5hmC |
fCAB-Seq | Sequencing 5fC |
CAB-Seq | Mapping 5caC |
CUT&TAG | Analyzing protein interactions with DNA |
CUT&RUN | Analyzing protein interactions with DNA |
