Table 3 Typical clinical trials targeting YAP/TAZ
From: Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets
Target | Intervention/treatment | Disease type | Phase | Current status | ClinicalTrials.gov identifier |
|---|---|---|---|---|---|
YAP | Simvastatin | Prostate cancer | 2 | Recruiting | NCT05586360 |
ION537 | Advanced solid tumors | 1 | Completed | NCT04659096 | |
YAP/TAZ | Zoledronate | Breast cancer | 2 | Terminated | NCT02347163 |
TEAD | IK-930 | Solid tumors | 1 | Recruiting | NCT05228015 |
