Fig. 3 | Signal Transduction and Targeted Therapy

Fig. 3

From: Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection

Fig. 3

Major pathways of glucose metabolism. Glycolysis, glycogenesis, phosphate pentose pathway, aerobic metabolism, and anaerobic metabolism are included. GLUT glucose transporter, Glc glucose, G6P glucose-6-phosphate, F6P fructose-6-phosphate, FBP fructose-1,6-biphosphate, GA3P glyceraldehyde-3-phosphate, DHAP dihydroxyacetone phosphate, 1,3BPG 1,3-biphosphoglycerate, 3PG 3-phosphoglycerate, 2PG 2-phosphoglycerate, PEP phosphoenolpyruvate, G1P glucose-1-phosphate, UDP-Glc uracil-diphosphate glucose, 6PGL 6-Phosphogluconolactone, 6PG 6-phosphogluconate, Ru5P ribulose-5-phosphate, R5P ribose-5-phosphate, Xu5P xylulose-5-phosphate, S7P Sedoheptulose-7-Phosphate, E4P erythrose-4-phosphate, HK hexokinase, GPI glucose-6-phosphate isomerase, PFK phosphofructokinase, ALD aldolase, GADPH glyceraldehyde-3-phosphate dehydrogenase, PGK phosphoglycerate kinase, PGM Phosphoglycerate mutase, PK pyruvate kinase, GS glycogen synthase, G6PD glucose-6-phosphate dehydrogenase, GNL gluconolactonase, 6PGDH 6-phosphogluconate dehydrogenase, R5PI ribose-5-phosphate isomerase, RPE ribulose-5-phosphate 3-epimerase, TK transketolase, TA transaldolase, LDH lactate dehydrogenase

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