Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human airway epithelium

Fig. 4

The relationship among the NQO1/VKORC1 expression, COVID-19 severity in patients and SARS-CoV-2 infection in cultured airway epithelial cells (AECs). The expression levels of NQO1 and VKORC1 in nasal brushing cells from COVID-19 patients were analyzed by single-cell RNA sequencing dataset (a–c). The correlation between NQO1/VKORC1 expression and SARS-CoV-2 N gene/protein expression in cultured AECs was analyzed by quantitative polymerase chain reaction (d–f) and immunofluorescence staining (g–j)

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