Table 1 Baseline characteristics

From: Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study

Parameter

A1 (%)

A2 (%)

B1 (%)

B2 (%)

Sex

    

 Male

8 (66.7)

10 (83.3)

14 (87.5)

10 (83.3)

 Female

4 (33.3)

2 (16.6)

2 (12.5)

2 (16.7)

 Age (median, range)

57 (29–71)

64 (43–78)

63 (22–73)

60.5 (48–72)

Performance status score

    

 0

2 (16.7)

0 (0)

1 (6.3)

2 (16.7)

 1

10 (83.3)

12 (100)

15 (93.7)

10 (83.3)

Pathological type

    

 Adenocarcinoma

5 (41.7)

2 (16.6)

5 (31.3)

2 (16.7)

 Squamous carcinoma

5 (41.7)

5 (41.7)

10 (62.5)

10 (83.3)

 Adenosquamous

0 (0)

2 (16.6)

0 (0)

0 (0)

 other

2 (16.6)

3 (25.0)

1 (6.2)

0 (0)

PD-L1 expression

    

 <1%

0 (0)

0 (0)

0 (0)

12 (100)

 1–49%

0 (0)

0 (0)

16 (100)

0 (0)

 ≥ 50%

12 (100)

12 (100)

0 (0)

0 (0)

Clinical stage

    

 IIa

0 (0)

0 (0)

1 (6.2)

1 (8.3)

 IIb

1 (8.3)

2 (16.6)

5 (31.3)

3 (25.0)

 IIIa

7 (58.3)

9 (75.0)

8 (50.0)

6 (50.0)

 IIIb

4 (33.3)

1 (8.3)

2 (12.5)

2 (16.7)

T stage

    

 1c

2 (16.6)

1 (8.3)

0 (0)

0 (0)

 2a

1 (8.3)

2 (16.6)

4 (25.0)

2 (16.7)

 2b

1 (8.3)

2 (16.6)

3 (18.8)

3 (25.0)

 3

8 (66.7)

5 (41.7)

7 (43.8)

5 (41.7)

 4

0 (0)

2 (16.6)

2 (12.5)

2 (16.7)

N stage

    

 0

0 (0)

0 (0)

3 (18.8)

2 (16.7)

 1

3 (25.0)

8 (66.7)

8 (50.0)

6 (50.0)

 2

9 (75.0)

4 (33.3)

5 (31.3)

4 (33.3)

M stage

    

 0

12 (100)

12 (100)

16 (100)

12 (100)