Fig. 7 | Signal Transduction and Targeted Therapy

Fig. 7

From: Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases

Fig. 7

Epigenetic and posttranslational modification of ferroptosis in CNS disease and CVD. AIS acute ischemic stroke, BAP1 BRCA1-associated protein 1, BMSC-Exos bone marrow mesenchymal stem cells (BMSCs)-derived exosomes, CVD cardiovascular diseases, DIC doxorubicin-induced cardiomyopathy, HFD High-fat diet, Egr-1 transcription factor early growth response-1, FSP1 ferroptosis suppressor protein 1, FTH1 ferritin heavy chain 1, METTL14 methyltransferase-like 14, ME2 malic enzyme 2, MIRI myocardial ischemia/reperfusion injury, MPP+ 1-methyl-4-phenylpyridinium, MS multiple sclerosis, MSCs-exo mesenchymal stem cells-derived exosomes, NAMPT nicotinamide phosphoribosyltransferase, NHLRC1 NHL repeat-containing 1, Ptgs2 prostaglandin-endoperoxide synthase-2, TBI traumatic brain injury, SIC sepsis-induced cardiomyopathy, SPATA2 Spermatogenesis-associated protein 2, TfR1 transferrin receptor 1, TMEM43 transmembrane protein 43

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