Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Aptamers targeting SARS-CoV-2 nucleocapsid protein exhibit potential anti pan-coronavirus activity

Fig. 1

Identification of aptamers of SARS-CoV-2 N protein with high neutralization activity. a Schematic diagram of magnetic bead screening aptamers. b The retention rate of five rounds of screening aptamers using SARS-CoV-2 NP. c Detection of library affinity using SPR (Surface plasmon resonance). d Preliminary screening of the antiviral effects of 165 aptamers against authentic SARS-CoV-2, 6 of 165 aptamers were selected for further evaluation. e The screening details and sequences of 6 selected aptamers. f The secondary structures of six aptamers using NUPACK software

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