Table 1 The relationship between CHRNA5 expression level and the clinical characteristics in ICC
From: Alpha5 nicotine acetylcholine receptor subunit promotes intrahepatic cholangiocarcinoma metastasis
Clinical pathological characteristics | CHRNA5 | χ value | p value | ||
---|---|---|---|---|---|
Low | High | ||||
Gender | Male | 32 | 21 | 0.738 | 0.4693 |
Female | 39 | 35 | |||
Age | ≤55 | 33 | 23 | 0.371 | 0.334 |
>55 | 38 | 33 | |||
Total bilirubin | ≤21 | 61 | 47 | 0.097 | 0.473 |
>21 | 10 | 9 | |||
Alanine transaminase | ≤40 | 55 | 34 | 4.189 | 0.032 |
>40 | 16 | 22 | |||
γ-glutamyl transpeptidas | ≤45 | 32 | 21 | 0.738 | 0.249 |
>45 | 39 | 35 | |||
Tumor Size | ≤6 | 36 | 37 | 3.025 | 0.059 |
>6 | 35 | 19 | |||
Lymph node metastasis | Negative | 49 | 20 | 13.991 | <0.005 |
Positive | 22 | 36 | |||
Differentiation | Well, moderate | 43 | 36 | 0.185 | 0.404 |
Poor | 28 | 20 | |||
TNM phase | I–II | 46 | 16 | 16.435 | <0.005 |
III–IV | 25 | 40 |