Fig. 3 | Signal Transduction and Targeted Therapy

Fig. 3

From: Efficacy and safety of PD-1 blockade plus long-course chemoradiotherapy in locally advanced rectal cancer (NECTAR): a multi-center phase 2 study

Fig. 3

Clinical efficacy. a Swimmer plot of 46 patients who reached the primary endpoint in this trial. b Representative radiographic image, endoscopic, specimen, and pathological image in patients of TRG 0 and 3. The white arrows represent the lesion sites. c Waterfall plot of maximum percent change in tumor size from baseline as measured according to RECIST v1.1. d Changes of pre-treatment cT and cN stage to post-treatment ypT and ypN stage in 46 patients who reached the primary endpoint. e Dynamic alteration of folate receptor-positive circulating tumor cells (FR+ CTCs) levels at pre-neoadjuvant (Pre) and before surgery (Post). The median and interquartile range are shown for each group

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