Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Drug repurposing for cancer therapy

Fig. 1

Tumoroids model in drug repurposing. a Schematic showing the generation of patient-derived organoids (PDOs) from a cancer biopsy: enzymatic digestion, embedding in extracellular matrix, addition of growth medium and cancer tumoroids enrichment by media compound withdrawal and/or addition of mutation related inhibitors. b, c The tumoroid model is used to screen drug repurposing candidates, resulting in the identification of drugs for preclinical and clinical testing. This figure was created with Biorender.com

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