Fig. 1

Biochemical synthesis and maturation of BAs. Schematic diagram depicting the biochemical synthesis of BAs. A prefix of G represents a glycine conjugate, while a prefix of T represents a taurine conjugate. Far left and far right labels describe the enzymatic reactions shown parallel within the tree. Top numbering keeps track of which conjugated primary BAs become which secondary BAs. This figure was created with BioRender.com