Fig. 1 | Signal Transduction and Targeted Therapy

Fig. 1

From: Cholangiocarcinoma combined with biliary obstruction: an exosomal circRNA signature for diagnosis and early recurrence monitoring

Fig. 1

Summary of cohort recruitment and sample acquisition. a A pilot cohort and a discovery cohort were prospectively recruited during April 2022 and June 2022 to identify CCA-BO-specific exosomal circRNAs. A training cohort and a validation cohort were retrospectively analyzed for model establishment and verification. b Serum samples were acquired from all recruited patients while bile samples were acquired from patients undergoing biliary drainage, followed by exosome isolation

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