Fig. 2

Sensitive groups or structures in stimuli-responsive hydrogel. This schematic summarizes the current responsive designs used in hydrogels for advanced therapies, including ROS-responsive, pH-responsive, and thermo-responsive designs, among others, and it also lists representative groups (e.g., boronic esters used in ROS-responsive designs) and structures (e.g., microbubbles used in ultrasound-responsive designs) used in these respective responsive designs. (Abbreviation: DMAA N,N-dimethyl acrylamide). Information is collected from published work.23,40,43,46,47,819,820,821,822 Adobe Illustrator was used to generate this figure