Fig. 1

The timescale and historical development of hyperuricemia (depicted in light red) and hyperuricemia treatment (depicted in dark red) from 1944 to June 2024, along with the volume of published literature, have been analyzed using data extracted from PubMed. The search criteria included “hyperuricemia*“ in conjunction with terms such as “history”, “medicine”, “treatment”, “therapy”, “drug”, “mechanism”, “genetic”, and “uric acid”