Fig. 3

The meaning of adaptive genome. Human sperm and egg form the innate human genome. Microbes, through various selections, become the adaptive genome. Adaptive genomes may adapt to host selection and regulation, the dynamics of established microbial communities (which may promote, inhibit or remain neutral),698,699,700 exposure to different diets and drugs, and fluctuations in the external environment. DASH: Dietary Approaches to Stop Hypertension