Fig. 6 | Signal Transduction and Targeted Therapy

Fig. 6

From: Human adipose and umbilical cord mesenchymal stem cell-derived extracellular vesicles mitigate photoaging via TIMP1/Notch1

Fig. 6

Histological analysis and inflammation antibody array of the dorsal skin in nude mice after UVB irradiation and EV treatment. a Representative images of Masson’s staining (scale bar, 50 μm). b Representative images of picrosirius red staining (scale bar, 50 μm). c Quantitation of collage area from Masson’s staining statistics. n = 6, **P < 0.01, ***P < 0.001. d Quantitation of collage area from picrosirius red staining statistics. n = 6, ***P < 0.001. e Western blot analysis for COL1, COL3, TIMP1, MMP1 and MMP3. f The top inflammatory factors examined by Inflammation Antibody Array. g Heatmap highlighting the representative inflammatory factors examined by the Inflammation Antibody Array. h Western blot analysis for inflammatory factors IL-1β, IL-6, TNF-α, and GM-CSF

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