Fig. 3

Neutralization activity of cRBD-induced antibodies against each strain. Geometric mean titer (GMT) of serum nAbs for authentic virus (a–c) (n = 5) and pseudovirus (d–f) (n = 3) 21 days after the third immunization (day 63 in Fig. 2a) for each group. Specific GMT values are presented in Supplementary Figs. 3–4. For ease of visualization, the cRBD1-3 results are plotted separately, and the results for the BA.1 RBD group are added as a control in each plot