Fig. 7 | Signal Transduction and Targeted Therapy

Fig. 7

From: A protein vaccine of RBD integrated with immune evasion mutation shows broad protection against SARS-CoV-2

Fig. 7

Analysis of BCR sequencing results. a Cumulative histogram of the proportion of each isoform of IGH in each group. b Statistical plot of the diversity of IGH isoforms in each group, using D50 as an indicator, with larger D50 values indicating greater diversity of IGH in the samples. c Expression levels of top-10 used V-J pairs in IgM. d Statistical analysis of the expression levels of the top 10 V-J genes associated with IgM in each group. e Expression levels of the top 10 V-J pairs used for IgD. f Statistical analysis of the expression levels of the top 10 V-J genes associated with IgD in each group. Statistical analysis was conducted using multiple tests and corrected for FDR, with Scheffe post hoc tests. *P < 0.05, **P < 0.01, ***P < 0.005. ns no significant. n = 3 in each group

Back to article page