Fig. 3 | Signal Transduction and Targeted Therapy

Fig. 3

From: Comparison of drug-eluting bead transarterial chemoembolization combined with apatinib versus drug-eluting bead transarterial chemoembolization for the treatment of unresectable hepatocellular carcinoma: a randomized, prospective, multicenter phase III trial

Fig. 3

Images in a 59-year-old man with advanced hepatocellular carcinoma. a Hepatic angiography during the first TACE. b In the first DEB-TACE, CalliSpheres@ Beads with a diameter of 100-300 um loaded with 60 mg of doxorubicin were used to embolize the right hepatic artery, and the VL phenomenon occurred in the re-examination angiography (arrow). c PVA particles with a diameter of 350-560 μm were subsequently added for embolization until the VL phenomenon disappeared in the re-examination angiography. d Enhanced MRI at 4 weeks after the first DEB-TACE revealed partial contrast enhancement in the peripheral intrahepatic lesion, suggesting a partial response according to mRECIST criteria. Each small division on the scale bar represents 1 cm. e After 3 rounds of DEB-TACE plus apatinib, MR images at 6 months of follow-up show that the tumor had a complete response. Each small division on the scale bar represents 1 cm. f One-year follow-up MR images show that the tumor had a complete response. Each small division on the scale bar represents 1 cm

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