Fig. 1
From: Bridge over troubled cells: bone marrow stromal cells transfer mitochondria to boost T cells
a Building on mitochondrial transfer techniques described in the literature, Baldwin and colleagues introduce a method to fortify CD8+ T cells with mitochondria transferred through tunneling nanotubules from bone marrow stromal cells (BMSCs). b The transfer results in T cells being more resistant against exhaustion and having higher anti-tumor activity in-vitro and in-vivo. c This could be applied to improve adoptive T cell therapies to treat patients with cancer. (Created with BioRender.com)
