Table 1 Correlation between Akkermansia muciniphila and clinicopathological parameters

From: Gut dysbiosis conveys psychological stress to activate LRP5/β-catenin pathway promoting cancer stemness

Factor

A. muciniphila high

A. muciniphila low

P value

NO.

%

NO.

%

All patients

28

49.1

29

50.9

 

Age, years

    

1

≤54

15

50

15

50

 

>54

13

48.1

14

51.9

 

Tumor size, cm

    

0.9

≤1

15

51.7

14

48.3

 

>1

13

46.4

15

53.6

 

Node status

    

1

Negative

9

50

9

50

 

Positive

19

48.7

20

51.3

 

Distant metastasis

    

0.005

Negative

22

66.7

11

33.3

 

Positive

6

25

18

75

 

Stage

    

0.005

I or II

22

66.7

11

33.3

 

III

6

25

18

75

 

ER status

    

1

Negative

7

70

3

30

 

Positive

21

44.7

26

55.3

 

PR status

    

0.4

Negative

7

63.6

4

36.4

 

Positive

20

44.4

25

55.6

 

Missing

1

    

HER2 status

    

1

Negative

3

42.9

4

57.1

 

Positive

23

47.9

25

52.1

 

Missing

2

    

Ki67 status

    

1

≤0.3

14

50

14

50

 

>0.3

10

50

10

50

 

Missing

4

 

5

  

CA153, U/mL

    

<0.0001

≤9.48

22

75.9

7

24.1

 

>9.48

6

21.4

22

78.6

 
  1. Statistical significance was determined by Pearson’s Chi-squared (χ2) test and Fisher’s Exact Test (ER status and HER2 status)